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It's a vicious game of cat and mouse: relentless FBI agent Frank LaCrosse steps outside his job to find the brilliant but nameless killer who has kidnapped his son. For over a year, he has been tracking the murderer across the country, but when the stakes become personal, he is removed from the case. Against orders from the Bureau, he continues his deadly manhunt. When a series of murders occurs in his district, a seasoned Amarillo sheriff finds himself torn between winning re-election and helping LaCrosse stay on the trail of the killer. From a death-filled motel room in Amarillo, to a snow-choked train pass through the Rockies, LaCrosse follows the tracks of a former railroad man and a mysterious young hitchhiker, one of whom may hold the secret of the search.