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Swamp Thing follows Dr. Abby Arcane as she investigates a deadly swamp-born virus in the small town of Marais, Louisiana. When a mysterious creature emerges from the murky marsh, she finds herself facing the nightmares of a supernatural world where no one is safe. With nature wildly out of balance and coming for the people of Marais, in the end, it may take some Thing from the swamp to save it.