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Between 8th Ave. and the Hudson River, the Irish mafia runs 20 blocks of a tough New York City neighborhood known as Hell's Kitchen. But for mob wives Kathy (Melissa McCarthy), Ruby (Tiffany Haddish) and Claire (Elizabeth Moss), things are about to take a dramatic and radical turn. When the FBI sends their husbands to prison, the three women take business into their own hands by running the rackets and taking out the competition.