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Their work is their passion.
William Masters and Virginia Johnson are known as pioneers of the science of human sexuality. Their research shoots them to fame on a trajectory that takes them from humble beginnings in the Midwest to the cover of Time magazine. Masters is a brilliant scientist who is out of touch with his own feelings. Johnson is a divorced mother who is ahead of her time on many fronts, including her determination to have a meaningful career. The pair's relationship isn't just professional, as it evolves into a three-way "marriage" with Masters' wife, Libby. "Masters of Sex" is based on Thomas Maier's book of the same name, which profiled the pair.
Popular guest stars include Annaleigh Ashford, Teddy Sears, Camryn Manheim, Rich Sommer, Barry Watson, Tate Donovan, Barry Bostwick, Peri Gilpin, Greg Grunberg, Josh Charles, Sterling K. Brown, Judy Greer, Mae Whitman, Sara Silverman and more!