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Immediately recognizable by his distinctive silver mask, the heroic wrestler known as El Santo ('The Saint') was Mexico's most popular luchador, becoming a folk hero and the star of a hugely popular series of action films. Santo vs. Evil Brain (Santo contra cerebro del mal) was the earliest cinematic excursion for this icon of Mexican popular culture.
The dastardly Doctor Campos is kidnapping and brainwashing scientists, and when undercover detective Santo falls prey to his scheme, Lieutenant Zambrano (Enrique Zambrano) and El Incognito (Fernando Osés) must come to his assistance, and foil Campos' plans.
Made back-to-back with Santo vs. Infernal Men, and shot in Cuba in the final days before Fidel Castro entered Havana, this film represents the celluloid birth of a true screen legend, and spawned a further fifty Santo films.
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